Physicochemical Properties of Characterization of PVP/CA/AE Nanofiber

Meuretta Alawiyah Pulungan, Ida Sriyanti, Leni Marlina


Nanofibers are nanotechnologies with cross-sectional diameters ranging from tens to hundreds of nanometers. We explained the definition of nanofibers and their unique physicochemical characteristics. This study aimed to see the characterization of Polyvinyl pyrrolidone/Cellulose acetate/Aloe vera extract fiber. The fiber was made with a concentration of PVP/CA in 13% (w/w) and an Aloe vera extract in 10% (w/w) using the electrospinning method. The electrospinning technique involves an electrohydrodynamic process in which liquid polymer droplets are electrified to produce jets that elongate to produce fibers. Electrospinning is an easy, fast, and simple technique for producing fibers with sizes ranging from micrometers to nanometers. Process parameters used in this research, such as flow rate of 0,20 ml/hour, high voltage of 12 kV, and drum speed is 200 rpm with the distance to the needle tip of the collector is 75 cm. The result showed that fiber PVP/CA/AE morphology is bead free and homogeneous. The average diameter of PVP/CA/AE fibers was 1115 nm.These results indicate that the resulting fiber is in the form of nanofibers. A small fiber diameter will result in a broader surface area. The XRD result shows that the PVP/CA/AE fibers have a semi-crystal phase.


Cellulose acetate; Electrospinning; Morphology; Nanotechnology; Polyvinylpyrrolidone

Full Text:



Aghamohamadi, N., Sanjani, N. S., Majidi, R. F., & Nasrollahi, S. A. (2018). Preparation and characterization of Aloe Vera acetate and electrospinning fibers as promising antibacterial properties materials. Materials Science & Engineering C, 1–26.

Alim Bahmid, N., Syamsu, K., & Maddu, A. (2014). Pengaruh Ukuran Serat Selulosa Asetat Dan Penambahan Dietilen Glikol (Deg) Terhadap Sifat Fisik Dan Mekanik Bioplastik Influence of Cellulose Acetate Fibers Size and Diethylen Glikol (Deg) Addition on Physical and Mechanical Properties of Bioplastics. Jurnal Teknologi Industri Pertanian, 24(3), 226–234.

Almafie, M. R., Nawawi, Z., Jauhari, J., & Sriyanti, I. (2020). Electrospun of Poly (vinyl alcohol)/Potassium hydroxide (PVA/KOH) nanofiber composites using the electrospinning method. IOP Conference Series: Materials Science and Engineering, 850(1), 0–7.

Barkalina, N., Charalambous, C., Jones, C., & Coward, K. (2014). Nanotechnology in reproductive medicine: Emerging applications of nanomaterials. Nanomedicine: Nanotechnology, Biology, and Medicine, 10(5), e921–e938.

Bhatnagar, A., Tripathi, M., Shalu, & Prajapati, A. (2022). Nanotechnology for Batteries. Materials Horizons: From Nature to Nanomaterials, January, 29–48.

Bhattacharya, D., Ghosh, B., & Mukhopadhyay, M. (2019). Development of nanotechnology for advancement and application in wound healing: A review. IET Nanobiotechnology, 13(8), 778–785.

Bonan, R. F., Bonan, P. R. F., Batista, A. U. D., Sampaio, F. C., Albuquerque, A. J. R., Moraes, M. C. B., Mattoso, L. H. C., Glenn, G. M., Medeiros, E. S., & Oliveira, J. E. (2015). In vitro antimicrobial activity of solution blow spun poly(lactic acid)/polyvinylpyrrolidone nanofibers loaded with Copaiba (Copaifera sp.) oil. Materials Science and Engineering C, 48, 372–377.

Chen, C., Tang, Y., Vlahovic, B., & Yan, F. (2017). Electrospun Polymer Nanofibers Decorated with Noble Metal Nanoparticles for Chemical Sensing. Nanoscale Research Letters, 12.

Dai, X. Y., Nie, W., Wang, Y. C., Shen, Y., Li, Y., & Gan, S. J. (2012). Electrospun emodin polyvinylpyrrolidone blended nanofibrous membrane: A novel medicated biomaterial for drug delivery and accelerated wound healing. Journal of Materials Science: Materials in Medicine, 23(11), 2709–2716.

Dong, W. H., Liu, J. X., Mou, X. J., Liu, G. S., Huang, X. W., Yan, X., Ning, X., Russell, S. J., & Long, Y. Z. (2020). Performance of polyvinyl pyrrolidone-isatis root antibacterial wound dressings produced in situ by handheld electrospinner. Colloids and Surfaces B: Biointerfaces, 188(November 2019), 110766.

Fatehi, P., & Abbasi, M. (2020). Medicinal plants used in wound dressings made of electrospun nanofibers. Journal of Tissue Engineering and Regenerative Medicine, 14(11), 1527–1548.

Gizaw, M., Thompson, J., Faglie, A., Lee, S. Y., Neuenschwander, P., & Chou, S. F. (2018). Electrospun fibers as a dressing material for drug and biological agent delivery in wound healing applications. Bioengineering, 5(1), 1–28.

Hou, J., Wang, Y., Xue, H., & Dou, Y. (2018). Biomimetic growth of hydroxyapatite on electrospun CA/PVP core-shell nanofiber membranes. Polymers, 10(9).

Huang, W., Wang, M. J., Liu, C. L., You, J., Chen, S. C., Wang, Y. Z., & Liu, Y. (2014). Phase separation in electrospun nanofibers controlled by crystallization induced self-assembly. Journal of Materials Chemistry A, 2(22), 8416–8424.

Hulupi, M., & Haryadi. (2018). Sintesis dan Karakterisasi Serat Nano Polivinil Alkoholyang Diikat Silang dengan Glutaraldehiduntuk Aplikasi Pembalut Luka. Chimica at Natura Acta, 6(3), 101–105.

Jauhari, J., Wiranata, S., Rahma, A., Nawawi, Z., & Sriyanti, I. (2019). Polyvinylpyrrolidone / Cellulose Acetate nanofibers synthesized using electrospinning method and their characteristics Polyvinylpyrrolidone / cellulose acetate nano fi bers synthesized using electrospinning method and their characteristics. Materials Research Express, 6(6), 64002.

Kamaruddin, Sriyanti, I., Edikresnha, D., Munir, M. M., & Khairurrijal, K. (2018). Electrosprayed Polyvinylpyrrolidone (PVP) Submicron Particles Loaded by Green Tea Extracts. IOP Conference Series: Materials Science and Engineering, 367(1).

Khoshnevisan, K., Maleki, H., Samadian, H., Shahsavari, S., Sarrafzadeh, M. H., Larijani, B., Dorkoosh, F. A., Haghpanah, V., & Khorramizadeh, M. R. (2018). Cellulose acetate electrospun nanofibers for drug delivery systems: Applications and recent advances. Carbohydrate Polymers, 198, 131–141.

Kurakula, M., & Rao, G. S. N. K. (2020). Pharmaceutical assessment of polyvinylpyrrolidone (PVP): As excipient from conventional to controlled delivery systems with a spotlight on COVID-19 inhibition. Journal of Drug Delivery Science and Technology, 60(August), 102046.

Liang, J., Cui, L., Li, J., Guan, S., Zhang, K., & Li, J. (2020). Aloe vera : A Medicinal Plant Used in Skin Wound Healing . Tissue Engineering Part B: Reviews, 1–67.

Marbelia, L., Bilad, M. R., & Vankelecom, I. F. J. (2019). Gradual PVP leaching from PVDF/PVP blend membranes and its effects on membrane fouling in membrane bioreactors. Separation and Purification Technology, 213(December 2018), 276–282.

Mir, M., Ali, M. N., Barakullah, A., Gulzar, A., Arshad, M., Fatima, S., & Asad, M. (2018). Synthetic polymeric biomaterials for wound healing: a review. Progress in Biomaterials, 7(1), 1–21.

Polini, A., & Yang, F. (2017). Physicochemical characterization of nanofiber composites. In Nanofiber Composites for Biomedical Applications. Elsevier Ltd.

Rahma, A., Munir, M. M., Khairurrijal, Prasetyo, A., Suendo, V., & Rachmawati, H. (2016). Intermolecular Interactions and the Release Pattern of Electrospun Curcumin-Polyvinyl(pyrrolidone) Fiber. Biological and Pharmaceutical Bulletin, 39(2), 163–173.

Ramakrishna, S., Fujihara, K., Teo, W., Lim, T., & Zuwei, M. (2005). An Introduction to Electrospinning and Nanofibers. World Scientific Publishing Co. Pte. Ltd.

Ranjbar-Mohammadi, M. (2018). Characteristics of aloe vera incorporated poly(ε-caprolactone)/gum tragacanth nanofibers as dressings for wound care. Journal of Industrial Textiles, 47(7), 1464–1477.

Sahoo, M., Vishwakarma, S., Panigrahi, C., & Kumar, J. (2021). Nanotechnology: Current applications and future scope in food. Food Frontiers, 2(1), 3–22.

Shahzad, M. N., & Ahmed, N. (2010). Effectiveness of Aloe Vera Gel compared with 1% silver sulphadiazine cream as burn wound dressing in second degree burns. J Pak Med Assoc, 63(2), 225–230.

Sharma, P., Kharkwal, A. C., Kharkwal, H., Abdin, M. Z., & Varma, A. (2014). A review on pharmacological properties of aloe vera. International Journal of Pharmaceutical Sciences Review and Research, 29(2), 31–37.

Sosiati, H., Apriyanto, & Safarudin, A. R. (2020). The Properties of Nanofiber Membranes Made of Aloe Vera Gel Combined with Polyvinyl Alcohol. In Lecture Notes in Mechanical Engineering. Springer Singapore.

Sriyanti, I., Agustini, M. P., Jauhari, J., & Nawawi, Z. (2020). Electrospun Nylon-6 Nanofibers and Their Characteristics. 9(1), 9–19.

Sriyanti, I., Edikresnha, D., Rahma, A., Munir, M. M., Rachmawati, H., & Khairurrijal, K. (2017). Correlation between Structures and Antioxidant Activities of Polyvinylpyrrolidone/ Garcinia mangostana L. Extract Composite Nanofiber Mats Prepared Using Electrospinnin. Journal of Nanomaterials, 2017.

Sriyanti, I., & Jauhari, J. (2019). Synthesis of polyvinyl acetate (PVAc) fibers using needleless electrospinning technique with straight wire electrode. Journal of Physics: Conference Series, 1166(1).

Sriyanti, I., Marlina, L., & Jauhari, J. (2020). Optimization of The Electrospinning Process for Preparation of Nanofibers From Poly (Vinyl Alcohol) (PVA) and Chromolaena odorata L. Extrac (COE). Jurnal Pendidikan Fisika Indonesia, 16(1), 47–56.

Subbiah, T., Bhat, G. S., Tock, R. W., Parameswaran, S., & Ramkumar, S. S. (2004). Electrospinning of Nanofibers. 96(2), 557–569.

Xu, D., Samways, D. S. K., & Dong, H. (2017). Fabrication of self-assembling nanofibers with optimal cell uptake and therapeutic delivery efficacy. Bioactive Materials, 2(4), 260–268.

Yousefzadeh, M. (2017). Modeling and simulation of the electrospinning process. In Electrospun Nanofibers. Elsevier Ltd.



  • There are currently no refbacks.

Creative Commons License

Jurnal ilmiah pendidikan fisika Al-Biruni is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.